ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0020.12-3 | Genetics | ESPEYB20

12.3. Genetic effects on the timing of parturition and links to fetal birth weight

Sole-Navais Pol , Flatley Christopher , Steinthorsdottir Valgerdur , Vaudel Marc , Juodakis Julius , Chen Jing , Laisk Triin , LaBella Abigail L , Westergaard David , Bacelis …. Jonas , Zhang Ge , Jacobsson Bo

Brief summary: This maternal genome-wide meta-analysis of gestational duration (n=195 555) found 22 associated loci and an enrichment in genes expressed during labour. The related meta-analysis of preterm delivery (18 797 cases, 260 246 controls) revealed seven associated loci and large genetic similarities with gestational duration. Maternal alleles that increase gestational duration had a negative effect on birth weight.Preterm delivery is one...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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